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Identification of low-dose multidrug combinations for sunitinib-naive and pre-treated renal cell carcinoma

BACKGROUND: Combinations of drugs can improve the efficacy of cancer treatment, enable the reduction of side effects and the occurrence of acquired drug resistance. METHODS: We approached this challenge mathematically by using the validated technology called the Therapeutically Guided Multidrug Opti...

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Detalles Bibliográficos
Autores principales: Rausch, Magdalena, Weiss, Andrea, Achkhanian, Joanna, Rotari, Andrei, Nowak-Sliwinska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435198/
https://www.ncbi.nlm.nih.gov/pubmed/32439932
http://dx.doi.org/10.1038/s41416-020-0890-y