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Identification of low-dose multidrug combinations for sunitinib-naive and pre-treated renal cell carcinoma
BACKGROUND: Combinations of drugs can improve the efficacy of cancer treatment, enable the reduction of side effects and the occurrence of acquired drug resistance. METHODS: We approached this challenge mathematically by using the validated technology called the Therapeutically Guided Multidrug Opti...
Autores principales: | Rausch, Magdalena, Weiss, Andrea, Achkhanian, Joanna, Rotari, Andrei, Nowak-Sliwinska, Patrycja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435198/ https://www.ncbi.nlm.nih.gov/pubmed/32439932 http://dx.doi.org/10.1038/s41416-020-0890-y |
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