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A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation

Members of the Herpesviridae, including the medically important alphaherpesvirus varicella-zoster virus (VZV), induce fusion of the virion envelope with cell membranes during entry, and between cells to form polykaryocytes in infected tissues. The conserved glycoproteins, gB, gH and gL, are the core...

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Detalles Bibliográficos
Autores principales: Oliver, Stefan L., Xing, Yi, Chen, Dong-Hua, Roh, Soung Hun, Pintilie, Grigore D., Bushnell, David A., Sommer, Marvin H., Yang, Edward, Carfi, Andrea, Chiu, Wah, Arvin, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435202/
https://www.ncbi.nlm.nih.gov/pubmed/32811830
http://dx.doi.org/10.1038/s41467-020-17911-0