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A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation
Members of the Herpesviridae, including the medically important alphaherpesvirus varicella-zoster virus (VZV), induce fusion of the virion envelope with cell membranes during entry, and between cells to form polykaryocytes in infected tissues. The conserved glycoproteins, gB, gH and gL, are the core...
Autores principales: | Oliver, Stefan L., Xing, Yi, Chen, Dong-Hua, Roh, Soung Hun, Pintilie, Grigore D., Bushnell, David A., Sommer, Marvin H., Yang, Edward, Carfi, Andrea, Chiu, Wah, Arvin, Ann M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435202/ https://www.ncbi.nlm.nih.gov/pubmed/32811830 http://dx.doi.org/10.1038/s41467-020-17911-0 |
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