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Tumoral and paratumoral NK cells and CD8(+) T cells of esophageal carcinoma patients express high levels of CD47

In a limited number of human malignancies, anti-CD47 therapy leads to the rapid clearance of tumor cells by macrophages. In esophageal squamous cell carcinoma, anti-CD47 treatment has shown promising results in vitro. However, the CD47 expression pattern in tumor-infiltrating lymphocytes (TILs), whi...

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Detalles Bibliográficos
Autores principales: Strizova, Zuzana, Vachtenheim, Jiri, Snajdauf, Martin, Lischke, Robert, Bartunkova, Jirina, Smrz, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435266/
https://www.ncbi.nlm.nih.gov/pubmed/32811852
http://dx.doi.org/10.1038/s41598-020-70771-y