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Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis

Despite their emerging relevance to fully understand disease pathogenesis, we have as yet a poor understanding as to how biomechanical signals are integrated with specific biochemical pathways to determine cell behaviour. Mesothelial-to-mesenchymal transition (MMT) markers colocalized with TGF-β1-de...

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Detalles Bibliográficos
Autores principales: Strippoli, Raffaele, Sandoval, Pilar, Moreno-Vicente, Roberto, Rossi, Lucia, Battistelli, Cecilia, Terri, Michela, Pascual-Antón, Lucía, Loureiro, Marta, Matteini, Francesca, Calvo, Enrique, Jiménez-Heffernan, José Antonio, Gómez, Manuel José, Jiménez-Jiménez, Victor, Sánchez-Cabo, Fátima, Vázquez, Jesús, Tripodi, Marco, López-Cabrera, Manuel, del Pozo, Miguel Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435273/
https://www.ncbi.nlm.nih.gov/pubmed/32811813
http://dx.doi.org/10.1038/s41419-020-02822-1