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Anti-VCAM-1 and Anti-IL4Rα Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy

The surface protein overexpressed on cancer cells can be used as biomarkers for early detection of specific diseases. Anti-VCAM-1 and anti-IL4Rα DNA aptamers specific to VCAM-1 and IL4Rα receptors that are overexpressed in 4T1 tumor-bearing mice could be used as potential biomarker for both diagnost...

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Detalles Bibliográficos
Autores principales: Chinnappan, Raja, Al Faraj, Achraf, Abdel Rahman, Anas M., Abu-Salah, Khalid M., Mouffouk, Fouzi, Zourob, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435411/
https://www.ncbi.nlm.nih.gov/pubmed/32751068
http://dx.doi.org/10.3390/molecules25153437