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Chemometric Models of Differential Amino Acids at the Na(v)α and Na(v)β Interface of Mammalian Sodium Channel Isoforms

(1) Background: voltage-gated sodium channels (Na(v)s) are integral membrane proteins that allow the sodium ion flux into the excitable cells and initiate the action potential. They comprise an α (Na(v)α) subunit that forms the channel pore and are coupled to one or more auxiliary β (Na(v)β) subunit...

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Detalles Bibliográficos
Autores principales: Villa-Diaz, Fernando, Lopez-Nunez, Susana, Ruiz-Castelan, Jordan E., Salinas-Stefanon, Eduardo Marcos, Scior, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435598/
https://www.ncbi.nlm.nih.gov/pubmed/32756517
http://dx.doi.org/10.3390/molecules25153551