Design, Synthesis and Bioactive Evaluation of Oxime Derivatives of Dehydrocholic Acid as Anti-Hepatitis B Virus Agents

Oxime derivatives of dehydrocholic acid and its esters were designed for anti-hepatitis B virus (HBV) drugs according to principles of assembling active chemical fragments. Twelve compounds were synthesized from dehydrocholic acid by esterification and oxime formation, and their anti-hepatitis B vir...

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Detalles Bibliográficos
Autores principales: Wei, Zhuocai, Tan, Jie, Cui, Xinhua, Zhou, Min, Huang, Yunhou, Zang, Ning, Chen, Zhaoni, Wei, Wanxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435646/
https://www.ncbi.nlm.nih.gov/pubmed/32722086
http://dx.doi.org/10.3390/molecules25153359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435646/
https://www.ncbi.nlm.nih.gov/pubmed/32722086
http://dx.doi.org/10.3390/molecules25153359

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