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Design, Synthesis and Bioactive Evaluation of Oxime Derivatives of Dehydrocholic Acid as Anti-Hepatitis B Virus Agents

Oxime derivatives of dehydrocholic acid and its esters were designed for anti-hepatitis B virus (HBV) drugs according to principles of assembling active chemical fragments. Twelve compounds were synthesized from dehydrocholic acid by esterification and oxime formation, and their anti-hepatitis B vir...

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Detalles Bibliográficos
Autores principales:	Wei, Zhuocai, Tan, Jie, Cui, Xinhua, Zhou, Min, Huang, Yunhou, Zang, Ning, Chen, Zhaoni, Wei, Wanxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435646/ https://www.ncbi.nlm.nih.gov/pubmed/32722086 http://dx.doi.org/10.3390/molecules25153359

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