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[(99m)Tc]Tc-DB1 Mimics with Different-Length PEG Spacers: Preclinical Comparison in GRPR-Positive Models

Background: The frequent overexpression of gastrin-releasing peptide receptors (GRPRs) in human cancers provides the rationale for delivering clinically useful radionuclides to tumor sites using peptide carriers. Radiolabeled GRPR antagonists, besides being safer for human use, have often shown high...

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Detalles Bibliográficos
Autores principales: Kanellopoulos, Panagiotis, Lymperis, Emmanouil, Kaloudi, Aikaterini, de Jong, Marion, Krenning, Eric P., Nock, Berthold A., Maina, Theodosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435657/
https://www.ncbi.nlm.nih.gov/pubmed/32731473
http://dx.doi.org/10.3390/molecules25153418