From Riluzole to Dexpramipexole via Substituted-Benzothiazole Derivatives for Amyotrophic Lateral Sclerosis Disease Treatment: Case Studies

The 1,3-benzothiazole (BTZ) ring may offer a valid option for scaffold-hopping from indole derivatives. Several BTZs have clinically relevant roles, mainly as CNS medicines and diagnostic agents, with riluzole being one of the most famous examples. Riluzole is currently the only approved drug to tre...

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Detalles Bibliográficos
Autores principales: Mignani, Serge, Majoral, Jean-Pierre, Desaphy, Jean-François, Lentini, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435757/
https://www.ncbi.nlm.nih.gov/pubmed/32707914
http://dx.doi.org/10.3390/molecules25153320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435757/
https://www.ncbi.nlm.nih.gov/pubmed/32707914
http://dx.doi.org/10.3390/molecules25153320

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