Efficient Palladium-Catalyzed Synthesis of 2-Aryl Propionic Acids

A flexible two-step, one-pot procedure was developed to synthesize 2-aryl propionic acids including the anti-inflammatory drugs naproxen and flurbiprofen. Optimal results were obtained in the presence of the novel ligand neoisopinocampheyldiphenylphosphine (NISPCPP) (9) which enabled the efficient s...

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Detalles Bibliográficos
Autores principales: Neumann, Helfried, Sergeev, Alexey G., Spannenberg, Anke, Beller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435766/
https://www.ncbi.nlm.nih.gov/pubmed/32731527
http://dx.doi.org/10.3390/molecules25153421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435766/
https://www.ncbi.nlm.nih.gov/pubmed/32731527
http://dx.doi.org/10.3390/molecules25153421

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