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Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators

Multidrug resistance (MDR) in cancer is one of the main limitations for chemotherapy success. Numerous mechanisms are behind the MDR phenomenon wherein the overexpression of the ATP-binding cassette (ABC) transporter proteins P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidr...

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Detalles Bibliográficos
Autores principales: M. F. Gonçalves, Bruno, S. P. Cardoso, David, U. Ferreira, Maria-José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435859/
https://www.ncbi.nlm.nih.gov/pubmed/32722234
http://dx.doi.org/10.3390/molecules25153364