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New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking

Colchicine is a well-known anticancer compound showing antimitotic effect on cells. Its high cytotoxic activity against different cancer cell lines has been demonstrated many times. In this paper we report the syntheses and spectroscopic analyses of novel colchicine derivatives obtained by structura...

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Detalles Bibliográficos
Autores principales: Krzywik, Julia, Aminpour, Maral, Maj, Ewa, Mozga, Witold, Wietrzyk, Joanna, Tuszyński, Jack A., Huczyński, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435877/
https://www.ncbi.nlm.nih.gov/pubmed/32748887
http://dx.doi.org/10.3390/molecules25153540