Novel d-Annulated Pentacyclic Steroids: Regioselective Synthesis and Biological Evaluation in Breast Cancer Cells

The acid-catalyzed cyclization of benzylidenes based on 16-dehydropregnenolone acetate (16-DPA) was studied. It was found that these compounds readily undergo regioselective interrupted Nazarov cyclization with trapping chloride ion and an efficient method of the synthesis of d-annulated pentacyclic...

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Detalles Bibliográficos
Autores principales: Vorontsova, Svetlana K., Yadykov, Anton V., Scherbakov, Alexander M., Minyaev, Mikhail E., Zavarzin, Igor V., Mikhaevich, Ekaterina I., Volkova, Yulia A., Shirinian, Valerii Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435891/
https://www.ncbi.nlm.nih.gov/pubmed/32752019
http://dx.doi.org/10.3390/molecules25153499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435891/
https://www.ncbi.nlm.nih.gov/pubmed/32752019
http://dx.doi.org/10.3390/molecules25153499

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