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Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis

Mycotoxins are considered one of the most dangerous agricultural and food contaminants. They are toxic and the development of rapid and sensitive analytical methods to detect and quantify them is a very important issue in the context of food safety and animal/human health. The need to detect mycotox...

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Autores principales: Colombo, Raffaella, Papetti, Adele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436008/
https://www.ncbi.nlm.nih.gov/pubmed/32751123
http://dx.doi.org/10.3390/molecules25153441
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author Colombo, Raffaella
Papetti, Adele
author_facet Colombo, Raffaella
Papetti, Adele
author_sort Colombo, Raffaella
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description Mycotoxins are considered one of the most dangerous agricultural and food contaminants. They are toxic and the development of rapid and sensitive analytical methods to detect and quantify them is a very important issue in the context of food safety and animal/human health. The need to detect mycotoxins at trace levels and to simultaneously analyze many different mycotoxin types became mandatory to protect public health. In fact, European Commission regulations specified both their limits in foodstuffs and official sample preparation protocols in addition to analytical methods to verify their presence. Capillary Electrophoresis (CE) includes different separation modes, allowing many versatile applications in food analysis and safety. In the context of mycotoxins, recent advances to improve CE sensitivity, particularly pre-concentration techniques or miniaturized systems, deserve remarkable attention, as they provide an interesting approach in the analysis of such contaminants in complex food matrices. This review summarizes the applications of CE combined with different pre-concentration approaches, which have been proposed in the literature (mainly) in the last ten years. A section is also dedicated to recent microchip–CE devices since they represent the most promising CE mode for this application.
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spelling pubmed-74360082020-08-24 Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis Colombo, Raffaella Papetti, Adele Molecules Review Mycotoxins are considered one of the most dangerous agricultural and food contaminants. They are toxic and the development of rapid and sensitive analytical methods to detect and quantify them is a very important issue in the context of food safety and animal/human health. The need to detect mycotoxins at trace levels and to simultaneously analyze many different mycotoxin types became mandatory to protect public health. In fact, European Commission regulations specified both their limits in foodstuffs and official sample preparation protocols in addition to analytical methods to verify their presence. Capillary Electrophoresis (CE) includes different separation modes, allowing many versatile applications in food analysis and safety. In the context of mycotoxins, recent advances to improve CE sensitivity, particularly pre-concentration techniques or miniaturized systems, deserve remarkable attention, as they provide an interesting approach in the analysis of such contaminants in complex food matrices. This review summarizes the applications of CE combined with different pre-concentration approaches, which have been proposed in the literature (mainly) in the last ten years. A section is also dedicated to recent microchip–CE devices since they represent the most promising CE mode for this application. MDPI 2020-07-29 /pmc/articles/PMC7436008/ /pubmed/32751123 http://dx.doi.org/10.3390/molecules25153441 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Colombo, Raffaella
Papetti, Adele
Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis
title Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis
title_full Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis
title_fullStr Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis
title_full_unstemmed Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis
title_short Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis
title_sort pre-concentration and analysis of mycotoxins in food samples by capillary electrophoresis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436008/
https://www.ncbi.nlm.nih.gov/pubmed/32751123
http://dx.doi.org/10.3390/molecules25153441
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