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Synthesis of Nucleobase-Modified RNA Oligonucleotides by Post-Synthetic Approach

The chemical synthesis of modified oligoribonucleotides represents a powerful approach to study the structure, stability, and biological activity of RNAs. Selected RNA modifications have been proven to enhance the drug-like properties of RNA oligomers providing the oligonucleotide-based therapeutic...

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Detalles Bibliográficos
Autores principales: Bartosik, Karolina, Debiec, Katarzyna, Czarnecka, Anna, Sochacka, Elzbieta, Leszczynska, Grazyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436257/
https://www.ncbi.nlm.nih.gov/pubmed/32717917
http://dx.doi.org/10.3390/molecules25153344