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Synthesis of Nucleobase-Modified RNA Oligonucleotides by Post-Synthetic Approach
The chemical synthesis of modified oligoribonucleotides represents a powerful approach to study the structure, stability, and biological activity of RNAs. Selected RNA modifications have been proven to enhance the drug-like properties of RNA oligomers providing the oligonucleotide-based therapeutic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436257/ https://www.ncbi.nlm.nih.gov/pubmed/32717917 http://dx.doi.org/10.3390/molecules25153344 |