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Novel Anticancer NHC*-Gold(I) Complexes Inspired by Lepidiline A

N-Heterocyclic carbene gold(I) complexes derived from 1,3-dibenzyl-4,5-diphenylimidazol-2-ylidene (NHC*) represent a promising class of anticancer drugs. Complexes of the type NHC*-Au-L (L = Br(−), I(−), C≡C-R) and [NHC*-Au-L](+) (L = NHC*, PPh(3)) have been synthesised. The X-ray crystal structures...

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Detalles Bibliográficos
Autores principales: Curran, Danielle, Müller-Bunz, Helge, Bär, Sofia I., Schobert, Rainer, Zhu, Xiangming, Tacke, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436326/
https://www.ncbi.nlm.nih.gov/pubmed/32751607
http://dx.doi.org/10.3390/molecules25153474