Rapamycin Inhibited Pyroptosis and Reduced the Release of IL-1β and IL-18 in the Septic Response

Pyroptosis, an inflammatory form of programmed cell death, is the initiating event of sepsis and results in immune imbalance by releasing IL-1β and IL-18 in the early stages. Studies show that enhancing autophagy via genetic manipulation can inhibit pyroptosis and prolong the survival of a sepsis an...

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Detalles Bibliográficos
Autores principales: Zhuo, Luo, Chen, Xiaobing, Sun, Yan, Wang, Yanli, Shi, Yuanfeng, Bu, Lin, Xia, Wei, Han, Jiayan, Chen, Dongmei, Li, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436330/
https://www.ncbi.nlm.nih.gov/pubmed/32851082
http://dx.doi.org/10.1155/2020/5960375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436330/
https://www.ncbi.nlm.nih.gov/pubmed/32851082
http://dx.doi.org/10.1155/2020/5960375

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