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Improved two-stage estimation to adjust for treatment switching in randomised trials: g-estimation to address time-dependent confounding
In oncology trials, control group patients often switch onto the experimental treatment during follow-up, usually after disease progression. In this case, an intention-to-treat analysis will not address the policy question of interest – that of whether the new treatment represents an effective and c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436445/ https://www.ncbi.nlm.nih.gov/pubmed/32223524 http://dx.doi.org/10.1177/0962280220912524 |