Rapamycin Pretreatment Alleviates Cerebral Ischemia/Reperfusion Injury in Dose-Response Manner Through Inhibition of the Autophagy and NFκB Pathways in Rats

Although rapamycin can attenuate cerebral ischemia/reperfusion (I/R) injury, the potential roles of rapamycin on cerebral I/R injury remain largely controversial. The present work aims to evaluate underlying molecular mechanisms of rapamycin pretreatment on I/R injury. In total, 34 Sprague-Dawley ra...

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Detalles Bibliográficos
Autores principales: Li, Liru, Huang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436792/
https://www.ncbi.nlm.nih.gov/pubmed/32874166
http://dx.doi.org/10.1177/1559325820946194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436792/
https://www.ncbi.nlm.nih.gov/pubmed/32874166
http://dx.doi.org/10.1177/1559325820946194

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