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Precision design of stable genetic circuits carried in highly‐insulated E. coli genomic landing pads

Genetic circuits have many applications, from guiding living therapeutics to ordering process in a bioreactor, but to be useful they have to be genetically stable and not hinder the host. Encoding circuits in the genome reduces burden, but this decreases performance and can interfere with native tra...

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Detalles Bibliográficos
Autores principales: Park, Yongjin, Espah Borujeni, Amin, Gorochowski, Thomas E, Shin, Jonghyeon, Voigt, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436927/
https://www.ncbi.nlm.nih.gov/pubmed/32812710
http://dx.doi.org/10.15252/msb.20209584