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Mitochondrion-mediated iron accumulation promotes carcinogenesis and Warburg effect through reactive oxygen species in osteosarcoma

BACKGROUND: Iron metabolism disorder is closely associated with several malignant tumors, however the mechanisms underlying iron and the carcinogenesis in osteosarcoma are not yet well understood. METHODS: Cell proliferation ability of osteosarcoma cell lines was measured by CCK-8, EdU incorporation...

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Detalles Bibliográficos
Autores principales: Ni, Shuo, Kuang, Yanbin, Yuan, Yin, Yu, Baoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437012/
https://www.ncbi.nlm.nih.gov/pubmed/32831652
http://dx.doi.org/10.1186/s12935-020-01494-3