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Coexistence of recurrent chromosomal abnormalities and the Philadelphia chromosome in acute and chronic myeloid leukemias: report of five cases and review of literature

Progression of chronic myelogenous leukemia (CML) is frequently accompanied by cytogenetic evolution. Additional genetic abnormalities are seen in 10–20% of CML cases at the time of diagnosis, and in 60–80% of cases of advanced disease. Unbalanced chromosomal changes such as an extra copy of the Phi...

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Detalles Bibliográficos
Autores principales: Gong, Jin-Ying, Zhang, Zhen-Hao, Zhang, Wei, Wang, Hui-Jun, Feng, Xiao-Fang, Zhou, Ji, Zhu, Guo-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437057/
https://www.ncbi.nlm.nih.gov/pubmed/32831907
http://dx.doi.org/10.1186/s13039-020-00501-6