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Discordance in 21-gene recurrence scores between paired breast cancer samples is inversely associated with patient age

BACKGROUND: The Oncotype DX 21-gene Recurrence Score is a genomic-based algorithm that guides adjuvant chemotherapy treatment decisions for women with early-stage, oestrogen receptor (ER)-positive breast cancer. However, there are age-related differences in chemotherapy benefit for women with interm...

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Detalles Bibliográficos
Autores principales: Bernhardt, Sarah M., Dasari, Pallave, Wrin, Joseph, Raymond, Wendy, Edwards, Suzanne, Walsh, David, Townsend, Amanda R., Price, Timothy J., Ingman, Wendy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437067/
https://www.ncbi.nlm.nih.gov/pubmed/32811558
http://dx.doi.org/10.1186/s13058-020-01327-1