Synergistic apoptosis following endoplasmic reticulum stress aggravation in mucinous colon cancer

BACKGROUND: Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticulum stress (ERS) aggravation in MCC would overwhelm compensatory cytoprotective...

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Detalles Bibliográficos
Autores principales: Dilly, Ashok K., Honick, Brendon D., Lee, Yong J., Bartlett, David L., Choudry, Haroon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437176/
https://www.ncbi.nlm.nih.gov/pubmed/32811515
http://dx.doi.org/10.1186/s13023-020-01499-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437176/
https://www.ncbi.nlm.nih.gov/pubmed/32811515
http://dx.doi.org/10.1186/s13023-020-01499-1

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