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Synergistic apoptosis following endoplasmic reticulum stress aggravation in mucinous colon cancer

BACKGROUND: Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticulum stress (ERS) aggravation in MCC would overwhelm compensatory cytoprotective...

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Detalles Bibliográficos
Autores principales:	Dilly, Ashok K., Honick, Brendon D., Lee, Yong J., Bartlett, David L., Choudry, Haroon A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437176/ https://www.ncbi.nlm.nih.gov/pubmed/32811515 http://dx.doi.org/10.1186/s13023-020-01499-1

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