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The Value of H3K27me3 Immunohistochemistry in Differentiating Malignant Peripheral Nerve Sheath Tumour with Its Histologic Mimickers

BACKGROUND: Diagnosis of malignant peripheral nerve sheath tumor (MPNST) is rather challenging due to its divergent morphologic heterogeneity and lack of specific ancillary test. The emergence of H3K27 trimethylation (H3K27me3) as a new immunohistochemistry (IHC) marker for MPNST have recently avail...

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Detalles Bibliográficos
Autores principales: Mustapar, Nurulhasanah, Zawawi, Muhamad Syahrul Fitri, Sharif, Sharifah Emilia Tuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437312/
https://www.ncbi.nlm.nih.gov/pubmed/32212796
http://dx.doi.org/10.31557/APJCP.2020.21.3.699