Amplifying immunogenicity of prospective Covid-19 vaccines by glycoengineering the coronavirus glycan-shield to present α-gal epitopes

The many carbohydrate chains on Covid-19 coronavirus SARS-CoV-2 and its S-protein form a glycan-shield that masks antigenic peptides and decreases uptake of inactivated virus or S-protein vaccines by APC. Studies on inactivated influenza virus and recombinant gp120 of HIV vaccines indicate that glyc...

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Detalles Bibliográficos
Autor principal: Galili, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author. Published by Elsevier Ltd. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437500/
https://www.ncbi.nlm.nih.gov/pubmed/32907757
http://dx.doi.org/10.1016/j.vaccine.2020.08.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437500/
https://www.ncbi.nlm.nih.gov/pubmed/32907757
http://dx.doi.org/10.1016/j.vaccine.2020.08.032

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