Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes

Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have enormous potential for the study of human cardiac disorders. However, their physiological immaturity severely limits their utility as a model system and their adoption for drug discovery. Here, we describe maturation media designed...

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Detalles Bibliográficos
Autores principales: M. Feyen, Dries A., McKeithan, Wesley L., N. Bruyneel, Arne A., Spiering, Sean, Hörmann, Larissa, Ulmer, Bärbel, Zhang, Hui, Briganti, Francesca, Schweizer, Michaela, Hegyi, Bence, Liao, Zhandi, Pölönen, Risto-Pekka, Ginsburg, Kenneth S., Lam, Chi Keung, Serrano, Ricardo, Wahlquist, Christine, Kreymerman, Alexander, Vu, Michelle, Amatya, Prashila L., Behrens, Charlotta S., Ranjbarvaziri, Sara, C. Maas, Renee G., Greenhaw, Matthew, Bernstein, Daniel, Wu, Joseph C., Bers, Donald M., Eschenhagen, Thomas, Metallo, Christian M., Mercola, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437654/
https://www.ncbi.nlm.nih.gov/pubmed/32697997
http://dx.doi.org/10.1016/j.celrep.2020.107925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437654/
https://www.ncbi.nlm.nih.gov/pubmed/32697997
http://dx.doi.org/10.1016/j.celrep.2020.107925

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