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Identification of the key gene and pathways associated with osteoarthritis via single-cell RNA sequencing on synovial fibroblasts

Osteoarthritis (OA) is a chronic degenerative joint disease with its onset closely related to the growth of synovial fibroblasts (SFs), yet the genes involved in are few reported. In our study, we aimed to identify the OA-associated key gene and pathways via the single-cell RNA sequencing (scRNA-seq...

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Detalles Bibliográficos
Autores principales: Wu, Zhen, Shou, Lu, Wang, Jian, Xu, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437759/
https://www.ncbi.nlm.nih.gov/pubmed/32872047
http://dx.doi.org/10.1097/MD.0000000000021707