Early Hippocampal Sharp-Wave Ripple Deficits Predict Later Learning and Memory Impairments in an Alzheimer’s Disease Mouse Model

Alzheimer’s disease (AD) is characterized by progressive memory loss, and there is a pressing need to identify early pathophysiological alterations that predict subsequent memory impairment. Hippocampal sharp-wave ripples (SWRs)—electrophysiological signatures of memory reactivation in the hippocamp...

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Detalles Bibliográficos
Autores principales: Jones, Emily A., Gillespie, Anna K., Yoon, Seo Yeon, Frank, Loren M., Huang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437815/
https://www.ncbi.nlm.nih.gov/pubmed/31747587
http://dx.doi.org/10.1016/j.celrep.2019.10.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437815/
https://www.ncbi.nlm.nih.gov/pubmed/31747587
http://dx.doi.org/10.1016/j.celrep.2019.10.056

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