Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development

Dysregulation of ribosome production can lead to a number of developmental disorders called ribosomopathies. Despite the ubiquitous requirement for these cellular machines used in protein synthesis, ribosomopathies manifest in a tissue-specific manner, with many affecting the development of the face...

Descripción completa

Detalles Bibliográficos
Autores principales: Farley-Barnes, Katherine I., Deniz, Engin, Overton, Maya M., Khokha, Mustafa K., Baserga, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437866/
https://www.ncbi.nlm.nih.gov/pubmed/32813698
http://dx.doi.org/10.1371/journal.pgen.1008967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437866/
https://www.ncbi.nlm.nih.gov/pubmed/32813698
http://dx.doi.org/10.1371/journal.pgen.1008967

Ejemplares similares