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A machine learning and network framework to discover new indications for small molecules

Drug repurposing, identifying novel indications for drugs, bypasses common drug development pitfalls to ultimately deliver therapies to patients faster. However, most repurposing discoveries have been led by anecdotal observations (e.g. Viagra) or experimental-based repurposing screens, which are co...

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Detalles Bibliográficos
Autores principales: Gilvary, Coryandar, Elkhader, Jamal, Madhukar, Neel, Henchcliffe, Claire, Goncalves, Marcus D., Elemento, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437923/
https://www.ncbi.nlm.nih.gov/pubmed/32764756
http://dx.doi.org/10.1371/journal.pcbi.1008098