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Mechanistic insights into Lhr helicase function in DNA repair

The DNA helicase Large helicase-related (Lhr) is present throughout archaea, including in the Asgard and Nanoarchaea, and has homologues in bacteria and eukaryotes. It is thought to function in DNA repair but in a context that is not known. Our data show that archaeal Lhr preferentially targets DNA...

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Detalles Bibliográficos
Autores principales: Buckley, Ryan J., Kramm, Kevin, Cooper, Christopher D. O., Grohmann, Dina, Bolt, Edward L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437997/
https://www.ncbi.nlm.nih.gov/pubmed/32706021
http://dx.doi.org/10.1042/BCJ20200379