Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium

Morphogens are important signalling molecules for tissue development and their secretion requires tight regulation. In the wing imaginal disc of flies, the morphogen Wnt/Wingless is apically presented by the secreting cell and re-internalized before final long-range secretion. Why Wnt molecules unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Linnemannstöns, Karen, Witte, Leonie, Karuna M, Pradhipa, Kittel, Jeanette Clarissa, Danieli, Adi, Müller, Denise, Nitsch, Lena, Honemann-Capito, Mona, Grawe, Ferdinand, Wodarz, Andreas, Gross, Julia Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438013/
https://www.ncbi.nlm.nih.gov/pubmed/32611603
http://dx.doi.org/10.1242/dev.185421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438013/
https://www.ncbi.nlm.nih.gov/pubmed/32611603
http://dx.doi.org/10.1242/dev.185421

Ejemplares similares