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Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium
Morphogens are important signalling molecules for tissue development and their secretion requires tight regulation. In the wing imaginal disc of flies, the morphogen Wnt/Wingless is apically presented by the secreting cell and re-internalized before final long-range secretion. Why Wnt molecules unde...
Autores principales: | Linnemannstöns, Karen, Witte, Leonie, Karuna M, Pradhipa, Kittel, Jeanette Clarissa, Danieli, Adi, Müller, Denise, Nitsch, Lena, Honemann-Capito, Mona, Grawe, Ferdinand, Wodarz, Andreas, Gross, Julia Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438013/ https://www.ncbi.nlm.nih.gov/pubmed/32611603 http://dx.doi.org/10.1242/dev.185421 |
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