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Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis

Pathogen-specific antibody responses need to be tightly regulated to generate protective but limit self-reactive immune responses. While loss of humoral tolerance has been associated with microbial infections, the pathways involved in balancing protective versus autoreactive antibody responses in hu...

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Detalles Bibliográficos
Autores principales: Danzer, Heike, Glaesner, Joachim, Baerenwaldt, Anne, Reitinger, Carmen, Lux, Anja, Heger, Lukas, Dudziak, Diana, Harrer, Thomas, Gessner, André, Nimmerjahn, Falk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438111/
https://www.ncbi.nlm.nih.gov/pubmed/32613944
http://dx.doi.org/10.7554/eLife.55319