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Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins

Polycomb silencing represses gene expression and provides a molecular memory of chromatin state that is essential for animal development. We show that Drosophila female germline stem cells (GSCs) provide a powerful system for studying Polycomb silencing. GSCs have a non-canonical distribution of PRC...

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Detalles Bibliográficos
Autores principales: DeLuca, Steven Z, Ghildiyal, Megha, Pang, Liang-Yu, Spradling, Allan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438113/
https://www.ncbi.nlm.nih.gov/pubmed/32773039
http://dx.doi.org/10.7554/eLife.56922