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A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome

Endoplasmic reticulum (ER) stress-mediated cell death is an emerging target for human chronic disorders, including neurodegeneration and diabetes. However, there is currently no treatment for preventing ER stress-mediated cell death. Here, we show that mesencephalic astrocyte-derived neurotrophic fa...

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Detalles Bibliográficos
Autores principales: Mahadevan, Jana, Morikawa, Shuntaro, Yagi, Takuya, Abreu, Damien, Lu, Simin, Kanekura, Kohsuke, Brown, Cris M., Urano, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438202/
https://www.ncbi.nlm.nih.gov/pubmed/32366942
http://dx.doi.org/10.1038/s41374-020-0436-1