Cargando…
A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome
Endoplasmic reticulum (ER) stress-mediated cell death is an emerging target for human chronic disorders, including neurodegeneration and diabetes. However, there is currently no treatment for preventing ER stress-mediated cell death. Here, we show that mesencephalic astrocyte-derived neurotrophic fa...
Autores principales: | Mahadevan, Jana, Morikawa, Shuntaro, Yagi, Takuya, Abreu, Damien, Lu, Simin, Kanekura, Kohsuke, Brown, Cris M., Urano, Fumihiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438202/ https://www.ncbi.nlm.nih.gov/pubmed/32366942 http://dx.doi.org/10.1038/s41374-020-0436-1 |
Ejemplares similares
-
Wolfram Syndrome iPS Cells: The First Human Cell Model of Endoplasmic Reticulum Disease
por: Urano, Fumihiko
Publicado: (2014) -
The Role of ER Stress in Diabetes: Exploring Pathological Mechanisms Using Wolfram Syndrome
por: Morikawa, Shuntaro, et al.
Publicado: (2022) -
Neuroimaging evidence of deficient axon myelination in Wolfram syndrome
por: Lugar, Heather M., et al.
Publicado: (2016) -
Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death
por: Clark, Amy L., et al.
Publicado: (2017) -
Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells
por: Stone, Stephen, et al.
Publicado: (2019)