A series of helical α-synuclein fibril polymorphs are populated in the presence of lipid vesicles

α-Synuclein (αS) deposition is a defining characteristic of Parkinson’s disease (PD) pathology, and other synucleinopathies. αS aggregates in disease, leading to the generation of neuronal inclusions known as Lewy bodies. These accumulate in the cytoplasmic space of dopaminergic neurons in the subst...

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Detalles Bibliográficos
Autores principales: Meade, Richard M., Williams, Robert J., Mason, Jody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438318/
https://www.ncbi.nlm.nih.gov/pubmed/32864427
http://dx.doi.org/10.1038/s41531-020-00122-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438318/
https://www.ncbi.nlm.nih.gov/pubmed/32864427
http://dx.doi.org/10.1038/s41531-020-00122-1

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