Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion

The mitochondrial permeability transition pore (mPTP) plays a critical role in the pathogenesis of cardiovascular diseases, including ischemia/reperfusion injury. Although the pore structure is still unresolved, the mechanism through which cyclophilin D (CypD) regulates mPTP opening is the subject o...

Descripción completa

Detalles Bibliográficos
Autores principales: Hurst, Stephen, Gonnot, Fabrice, Dia, Maya, Crola Da Silva, Claire, Gomez, Ludovic, Sheu, Shey-Shing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438327/
https://www.ncbi.nlm.nih.gov/pubmed/32814770
http://dx.doi.org/10.1038/s41419-020-02864-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438327/
https://www.ncbi.nlm.nih.gov/pubmed/32814770
http://dx.doi.org/10.1038/s41419-020-02864-5

Ejemplares similares