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High Molecular Weight ACTH-Precursor Presence in a Metastatic Pancreatic Neuroendocrine Tumor Causing Severe Ectopic Cushing's Syndrome: A Case Report

Ectopic ACTH-secretion causing Cushing's syndrome is unusual and its diagnosis is frequently challenging. The presence of high-molecular-weight precursors throughout pro-opiomelanocortin (POMC) translation by these tumors is often not reported. We present the case of a 49-year-old woman with a...

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Detalles Bibliográficos
Autores principales: Mehta, Roopa, Lam-Chung, César Ernesto, Hinojosa-Amaya, José Miguel, Roldán-Sarmiento, Paola, Guillen-Placencia, Maria Fernanda, Villanueva-Rodriguez, Gerladine, Juarez-Leon, Oscar Alfredo, Leon-Domínguez, Jefsi, Grajales-Gómez, Mariana, Ventura-Gallegos, Jose Luis, León-Suárez, Andrés, Gómez-Pérez, Francisco J., Cuevas-Ramos, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438413/
https://www.ncbi.nlm.nih.gov/pubmed/32903471
http://dx.doi.org/10.3389/fendo.2020.00557