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Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors

Intravenous immunoglobulin G (IVIgG) is approved for primary immunodeficiency syndromes but may induce anti-cancer effects, and while this has been attributed to its anti-inflammatory properties, IgG against specific tumor targets may play a role. We evaluated IVIgG alone, and with a Heat shock prot...

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Detalles Bibliográficos
Autores principales: Jones, Richard J., Singh, Ram K., Shirazi, Fazal, Wan, Jie, Wang, Hua, Wang, Xiaobin, Ha, Min Jin, Baljevic, Muhamed, Kuiatse, Isere, Davis, Richard E., Orlowski, Robert Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438474/
https://www.ncbi.nlm.nih.gov/pubmed/32903557
http://dx.doi.org/10.3389/fimmu.2020.01816