Cargando…

Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors

Intravenous immunoglobulin G (IVIgG) is approved for primary immunodeficiency syndromes but may induce anti-cancer effects, and while this has been attributed to its anti-inflammatory properties, IgG against specific tumor targets may play a role. We evaluated IVIgG alone, and with a Heat shock prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jones, Richard J., Singh, Ram K., Shirazi, Fazal, Wan, Jie, Wang, Hua, Wang, Xiaobin, Ha, Min Jin, Baljevic, Muhamed, Kuiatse, Isere, Davis, Richard E., Orlowski, Robert Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438474/ https://www.ncbi.nlm.nih.gov/pubmed/32903557 http://dx.doi.org/10.3389/fimmu.2020.01816

Ejemplares similares

Role of Heat Shock Proteins (HSP70 and HSP90) in Viral Infection
por: Lubkowska, Anna, et al.
Publicado: (2021)

Heat Shock Protein 90 (Hsp90) and Hsp70 as Potential Therapeutic Targets in Autoimmune Skin Diseases
por: Tukaj, Stefan, et al.
Publicado: (2022)

Y‐632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivo
por: Wang, Wenqian, et al.
Publicado: (2016)

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases
por: Lackie, Rachel E., et al.
Publicado: (2017)

Hsp70 and Hsp90 Elaborately Regulate RNAi Efficiency in Plutella xylostella
por: Lin, Sujie, et al.
Publicado: (2023)

Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma
por: Eugênio, Angela Isabel Pereira, et al.
Publicado: (2017)

Hsp70 and Hsp110 Chaperones Promote Early Steps of Proteasome Assembly
por: Matias, Ana C., et al.
Publicado: (2022)

Bacterial Hsp90 Facilitates the Degradation of Aggregation-Prone Hsp70–Hsp40 Substrates
por: Fauvet, Bruno, et al.
Publicado: (2021)

Hsp110 Chaperones Control Client Fate Determination in the Hsp70–Hsp90 Chaperone System
por: Mandal, Atin K., et al.
Publicado: (2010)

Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy
por: Tomasello, G., et al.
Publicado: (2011)

Modelling the Role of the Hsp70/Hsp90 System in the Maintenance of Protein Homeostasis
por: Proctor, Carole J., et al.
Publicado: (2011)

Characterization of a the Plasmodium falciparum Hsp70-Hsp90 organising protein
por: Gitau, Grace, et al.
Publicado: (2010)

Inhibition of Heat Shock proteins HSP90 and HSP70 induce oxidative stress, suppressing cotton fiber development
por: Sable, Anshulika, et al.
Publicado: (2018)

The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model
por: Gorska-Ponikowska, Magdalena, et al.
Publicado: (2020)

Genome-wide identification and expression analysis of the Hsp20, Hsp70 and Hsp90 gene family in Dendrobium officinale
por: Wang, Hongman, et al.
Publicado: (2022)

Assessment of heat shock protein (HSP60, HSP72, HSP90, and HSC70) expression in cultured limbal stem cells following air lifting
por: Ebrahimi, Marzeih, et al.
Publicado: (2010)

The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90
por: Alberti, Giusi, et al.
Publicado: (2022)

Characterisation of the Plasmodium falciparum Hsp70–Hsp90 organising protein (PfHop)
por: Gitau, Grace W., et al.
Publicado: (2011)

Nuclear HSP90 and HSP70 in COPD patients treated with formoterol or formoterol and corticosteroids
por: Holownia, A, et al.
Publicado: (2009)

The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage
por: Truman, Andrew W., et al.
Publicado: (2014)

HSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative Neoplasms
por: Sevin, Margaux, et al.
Publicado: (2015)

HSP70 and HSP90 in Cancer: Cytosolic, Endoplasmic Reticulum and Mitochondrial Chaperones of Tumorigenesis
por: Albakova, Zarema, et al.
Publicado: (2022)

Folding or holding?—Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease
por: Rutledge, Benjamin S., et al.
Publicado: (2022)

Regulation of Vascular Endothelial Cell Polarization and Migration by Hsp70/Hsp90-Organizing Protein
por: Li, Jingyu, et al.
Publicado: (2012)

Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis
por: Sitko, Krzysztof, et al.
Publicado: (2021)

HSP70 and HSP90 Differentially Regulate Translocation of Extracellular Antigen to the Cytosol for Cross-Presentation
por: Kato, Yu, et al.
Publicado: (2012)

Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90
por: Zhang, Guohua, et al.
Publicado: (2017)

Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer
por: Ruckova, Eva, et al.
Publicado: (2012)

Ameliorating cancer cachexia by inhibiting cancer cell release of Hsp70 and Hsp90 with omeprazole
por: Liu, Zhelong, et al.
Publicado: (2021)

Corrigendum: HSP70 and HSP90 in cancer: cytosolic, endoplasmic reticulum and mitochondrial chaperones of tumorigenesis
por: Albakova, Zarema, et al.
Publicado: (2023)

Characteristic and expression of Hsp70 and Hsp90 genes from Tyrophagus putrescentiae and their response to thermal stress
por: Wang, Jing, et al.
Publicado: (2021)

A Cytosolic Relay of Heat Shock Proteins HSP70-1A and HSP90β Monitors the Folding Trajectory of the Serotonin Transporter
por: El-Kasaby, Ali, et al.
Publicado: (2014)

Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage
por: Park, Sangkyu, et al.
Publicado: (2019)

Involvement of heat shock proteins HSP70 in the mechanisms of endogenous neuroprotection: the prospect of using HSP70 modulators
por: Belenichev, Igor F., et al.
Publicado: (2023)

Dexamethasone Regulates CFTR Expression in Calu-3 Cells with the Involvement of Chaperones HSP70 and HSP90
por: Prota, Luiz Felipe M., et al.
Publicado: (2012)

Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules
por: Röhl, Alina, et al.
Publicado: (2015)

MAPK1 of Leishmania donovani interacts and phosphorylates HSP70 and HSP90 subunits of foldosome complex
por: Kaur, Pavneet, et al.
Publicado: (2017)

The APE2 Exonuclease Is a Client of the Hsp70–Hsp90 Axis in Yeast and Mammalian Cells
por: Omkar, Siddhi, et al.
Publicado: (2022)

Characterization, and Functional Analysis of Hsp70 and Hsp90 Gene Families in Glyphodes pyloalis Walker (Lepidoptera: Pyralidae)
por: Ding, Jian-hao, et al.
Publicado: (2021)

Induction of heat shock protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun
por: Li, Chengyuan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_h4q4kn2mc8f1p441rli68n3g87