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Tisp40 Induces Tubular Epithelial Cell GSDMD-Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via NF-κB Signaling

Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). As a transcription factor, the Transcript induced in spermiogenesis 40 (Tisp40) has been found to be involved in renal IRI. However, the role of Tisp40 in tubular epithelial cell (TEC) pyroptosis of renal IRI rema...

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Detalles Bibliográficos
Autores principales: Xiao, Chengcheng, Zhao, Haijun, Zhu, Hai, Zhang, Yingyu, Su, Qiuju, Zhao, Feng, Wang, Renhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438479/
https://www.ncbi.nlm.nih.gov/pubmed/32903383
http://dx.doi.org/10.3389/fphys.2020.00906