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NLRP7 plays a functional role in regulating BMP4 signaling during differentiation of patient-derived trophoblasts

Complete hydatidiform mole (HM) is a gestational trophoblastic disease resulting in hyperproliferation of trophoblast cells and absence of embryo development. Mutations in the maternal-effect gene NLRP7 are the major cause of familial recurrent complete HM. Here, we established an in vitro model of...

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Detalles Bibliográficos
Autores principales: Alici-Garipcan, Aybuke, Özçimen, Burcu, Süder, Ilke, Ülker, Volkan, Önder, Tamer T., Özören, Nesrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438493/
https://www.ncbi.nlm.nih.gov/pubmed/32814763
http://dx.doi.org/10.1038/s41419-020-02884-1