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NLRP7 plays a functional role in regulating BMP4 signaling during differentiation of patient-derived trophoblasts
Complete hydatidiform mole (HM) is a gestational trophoblastic disease resulting in hyperproliferation of trophoblast cells and absence of embryo development. Mutations in the maternal-effect gene NLRP7 are the major cause of familial recurrent complete HM. Here, we established an in vitro model of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438493/ https://www.ncbi.nlm.nih.gov/pubmed/32814763 http://dx.doi.org/10.1038/s41419-020-02884-1 |